A new study by Italian researchers has found that topical cannabidiol
Scleroderma, also known as systemic sclerosis, is a rare autoimmune connective tissue and rheumatic disease characterized by the tightening of the skin and the narrowing of blood vessels. The condition causes an overproduction of collagen, leading to inflammation in the skin and other parts of the body. The narrowing of blood vessels can also cause skin ulcers of the fingertips known as digital ulcers. Common treatments used to treat scleroderma include medication, physical therapy and surgery.
In a randomized clinical trial, researchers at University Hospital of Modena, Italy compared the effectiveness of a
CBD Promoted Healing and Relieved Pain for Ulcers
Participants were asked to fill out a daily journal to record their symptoms for later analysis. The researchers determined that study participants in the CBD group saw better healing and greater pain relief than those in the control group.
“Although mean wound-related pain NRS [numeric rating scale] scores did not differ between CBD-treated patients and control patients at baseline, their mean scores differed significantly after 1 month,” the authors of the study wrote.
The authors of the study noted that 18 of the 25 (72%) patients treated with CBD experienced complete healing by the end of the study period. By contrast, complete healing was seen in only 6 of the 20 (30%) patients who used conventional treatments following surgery. The authors also noted that patients in the CBD group reported no adverse effects during the course of the study.
“The present study is the first to report the effectiveness of local CBD treatment in the management of SSc-DUs [systemic sclerosis digital ulcers],” the authors concluded. “Topical administration of CBD is a safe, effective, noninvasive tool that is associated with improved wound-related pain, DU healing, and QoL [quality of life] of patients with SSc.”
Last year, a randomized, placebo-controlled
In 2015, a